The Arizona Cardinals visit the Seattle Seahawks at Lumen Field on Sunday, November 8, at 4:25 p.m. ET. The matchup that should decide it is Arizona's passing game against a Seattle defense allowing just 169 passing yards a game. Rain and gusty wind in the forecast add another layer to a game the market expects to be low scoring.

The Matchup

Away: Arizona Cardinals (3-5; 0-3 home, 3-2 road)
Home: Seattle Seahawks (4-4; 3-2 home, 1-2 road)
Venue: Lumen Field, Seattle, WA
Kickoff: Sunday, November 8, 4:25 p.m. ET
TV: Fox
Line (DraftKings): SEA -8.5, O/U 39.5

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What Decides It

Seattle's pass defense is the matchup that should decide this game. Arizona throws for 239 yards a game, while Seattle allows only 169 through the air. That leaves the Cardinals' passing attack facing a defense that has held opponents well short of what Arizona normally produces.

The broader numbers back it up. Seattle allows 263 total yards and 20 points a game. The catch is personnel: defensive tackles Leonard Williams and Brandon Pili and linebacker Uchenna Nwosu are all listed out, so Seattle's defense will be shorthanded.

Arizona is a better team away from home, and that keeps this from being a formality. The Cardinals are 0-3 at home and 3-2 on the road. Their last two road games were both wins, 33-30 in overtime and 18-16.

Seattle, meanwhile, is coming off a 34-17 home loss in its most recent game. The Seahawks also face a soft spot on the ground: Arizona allows 122 rushing yards a game, more than the 110 Seattle averages. Emanuel Wilson's carries could matter as much as anything in the passing game.

The market is pricing in less scoring than either team's season rate suggests. Seattle averages 23 points and Arizona 22, a combined 45 a game, against a total of 39.5. The forecast calls for rain at Lumen Field with gusts to 23 mph and a 55% chance of precipitation.

Players to Watch

Arizona Cardinals

Passing: Gardner Minshew II – 17-23, 188 YDS, 3 TD
Rushing: Tyler Allgeier – 72 ATT, 323 YDS, 2 TD
Receiving: Trey McBride – 66 REC, 544 YDS, 5 TD

McBride is the volume piece of the Arizona passing game, and he is the player Seattle's secondary has to account for first.

Seattle Seahawks

Passing: Drew Lock – 35-48, 422 YDS, 4 TD
Rushing: Emanuel Wilson – 111 ATT, 403 YDS, 3 TD
Receiving: Jaxon Smith-Njigba – 64 REC, 985 YDS, 9 TD

Smith-Njigba has 9 receiving touchdowns and draws an Arizona defense allowing 238 passing yards a game, far more than Seattle gives up.

Injury Report

SEA Uchenna Nwosu (LB): Out – Ankle
SEA Leonard Williams (DT): Out – Shoulder
SEA Quenton Nelson (G): Out – Knee
SEA Brandon Pili (DT): Out – Back
SEA Rashid Shaheed (WR): Out – Knee
ARI Jon Gaines II (G): Out – Ankle
ARI Jayden Williams (OT): Out – Knee
ARI Walter Nolen III (DT): Questionable – Ankle
ARI Max Melton (CB): Questionable – Knee
ARI Bam Knight (RB): Out – Concussion

Weather

Conditions: Rain, 56°F
Wind: Gusts to 23 mph
Precipitation: 55% chance

Prediction

Seattle's defense, allowing 169 passing yards and 20 points a game, should keep Arizona's offense in check even with three defensive players listed out. Arizona's 3-2 road record and its 30 points allowed per game cut in opposite directions, but the road form is enough to keep it inside the number. Seattle wins, Arizona covers, and the game stays under.