The Las Vegas Raiders visit the San Francisco 49ers at Levi's Stadium on Sunday, November 8, at 4:25 p.m. ET. Las Vegas is 3-1 on the road and 1-3 at home. It walks into a building where San Francisco is 4-0.
The Matchup
Raiders: 4-4 (home 1-3, road 3-1)
49ers: 6-1 (home 4-0, road 2-1)
Venue: Levi's Stadium, Santa Clara, CA
Kickoff: Sunday, November 8, 4:25 p.m. ET
TV: Fox
Line (DraftKings): SF -10, O/U 51.5
Las Vegas Raiders at San Francisco 49ers tickets
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What Decides It
The 49ers' run game meets a Raiders run defense that gives up more than San Francisco usually gains. San Francisco runs for about 127 yards a game. Las Vegas allows about 146 on the ground.
Christian McCaffrey has 389 yards and 8 touchdowns on the ground. With Mike Evans, Christian Kirk and Deebo Samuel Sr. all out, expect San Francisco to lean on him and George Kittle.
The other side of that matchup favors San Francisco too. Las Vegas runs for only about 77 yards a game, and the 49ers allow about 89. Ashton Jeanty has 337 yards on 108 carries, which leaves the Raiders leaning on one dimension.
Kirk Cousins and the passing game are the Raiders' path to keeping this close. Las Vegas throws for about 273 yards a game against a 49ers defense allowing about 224. Through the air, the Raiders gain well more than San Francisco usually gives up.
Cousins has 19 touchdowns and 5 interceptions, and Brock Bowers has 547 receiving yards with 5 scores. San Francisco will defend him without cornerback Nate Hobbs, who is on injured reserve.
The Raiders' road form is real, but so is the 49ers' home record. Las Vegas has won three times away from home and once in its own stadium. Its lone win in the last five games came on the road, 38-33 last week.
San Francisco has not lost at home. Its only loss in the last five came on the road, 29-20. The 49ers also allow about 20 points a game, while the Raiders allow about 29.
Players to Watch
Las Vegas Raiders
Passing: Kirk Cousins – 180-283, 2,124 YDS, 19-5 (TD-INT)
Rushing: Ashton Jeanty – 108 ATT, 337 YDS, 1 TD
Receiving: Brock Bowers – 41 REC, 547 YDS, 5 TD
Bowers is the target to watch against a San Francisco secondary missing Hobbs.
San Francisco 49ers
Passing: Brock Purdy – 146-211, 1,748 YDS, 15-4 (TD-INT)
Rushing: Christian McCaffrey – 84 ATT, 389 YDS, 8 TD
Receiving: George Kittle – 34 REC, 425 YDS, 5 TD
McCaffrey should find room against the Raiders' front.
Injury Report
49ers: CB Nate Hobbs – Injured Reserve (groin); WR Demarcus Robinson – Injured Reserve (ankle); WR Mike Evans – Out (Achilles); WR Christian Kirk – Out (knee, meniscus); WR Deebo Samuel Sr. – Out (hamstring)
Raiders: CB Darien Porter – Questionable (groin); DT Thomas Booker IV – Out (ankle); DE Patrick Johnson – Injured Reserve (neck); DE Keyron Crawford – Injured Reserve (ankle); CB Chigozie Anusiem – Injured Reserve (knee)
The Raiders' absences hit the front that has to slow McCaffrey. San Francisco's hit the receiver room, which should push more of the offense toward the run.
Prediction
49ers 27, Raiders 23. San Francisco should control this on the ground, where its run game meets a Raiders defense allowing 146.4 rushing yards a game. Cousins and Bowers keep Las Vegas within reach, and the Raiders' road form says they cover the 10. The 49ers stay perfect at home.